Prof. Wim Vanden Berghe's lab of Epigenetic signalling

Our main goal is to identify epigenomic targets of medicinal natural compounds, steroid hormones and hypoxia mimetics in models of cancer-inflammation, cardiovascular disease and neuroplasticity. Therefore our approaches focus on:

• Applying systems biology to integrate epigenomic, transcriptomic, microRNomic, (chemo)proteomic datasets to identify key signalling pathways and molecular targets of medicinal phytochemicals.
• Characterize intracellular protein targets of phytochemicals with epigenome targeting properties on a proteome-wide scale
• Characterize the epigenetic role of steroid responsive microRNAs in hormone therapy responses in cancer-inflammation
• Describe the epigenetic modulator effects of different medicinal compounds in relation to therapy sensitivity (chemo/hormone resistance), cardioprotection, or cognitive functions

Contact us

You are very welcome to get in touch with us in

Tel: 032652318

Email: claudina.pereznovo@uantwerpen.be; wim.vandenberghe@uantwerpen.be

Website: https://www.uantwerpen.be/en/rg/ppes/

Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Lab of Proteinscience, Proteomics and Epigenetic Signalling, University of Antwerp, Campus Drie Eiken – Room S4.25, Universiteitsplein 1, 2610 Wilrijk, Belgium